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8.4 Baicalein mitigates secondary injury after TBI Baicalein is a bioactive flavone derived from the roots of Scutellaria baicalensis

CPP-CAND disrupts FOXO4-p53 foci and induces apoptosis through caspase-dependent pathways FOXO4 is progressively recruited to euchromatin foci following senescence induction and is retained in the nucleus of senescent cells through its interaction with p53, contributing to the maintenance of the senescent state 34

In contrast serum folate in the umbilical cord vein was reported to be around two times higher than in the maternal circulation (Reference Obeid, Munz and Jger55)